Effects and Safety of Botulinum Toxin Injection in Treatment of Androgenetic Alopecia: A Meta-Analysis and Systematic Review

    January 2025 in “ Dermatologic Surgery ”
    Fengrui Cheng, Xingrui Cai, Ying Zhang … Sisi Yin
    Studysummary This meta-analysis and systematic review found that botulinum toxin injections significantly increased hair count in patients with androgenetic alopecia compared to controls, indicating promising efficacy and good safety.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.lww.com →
    Discuss this study in the Community →

    Research cited in this study 18

    1. Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/Mir-506-3p/Bax Axis Aesthetic Plastic Surgery · 2024
    2. Assessment of Efficacy of Different Botulinum Toxin A Concentrations in the Treatment of Androgenetic Alopecia Assessed by Dermoscopy Journal of Cosmetic Dermatology · 2023
    3. A Study of Combination Unilateral Subcutaneous Botulinum Toxin A Treatment for Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    4. Efficacy of Botulinum Toxin A Injection in the Treatment of Androgenic Alopecia: A Comparative Controlled Study Journal of Cosmetic Dermatology · 2022
    5. The Effect of Botulinum Toxin on Hair Follicle Cell Regeneration Under Continuous Stress Conditions: A Pilot Animal Study Neurotoxicity Research · 2022
    6. Is There a Rationale for the Use of Botulinum Toxin in the Treatment of Androgenetic Alopecia? Journal of Cosmetic Dermatology · 2021
    7. Therapeutic Effect of Botulinum Toxin on Scalp Alopecia: Physiopathology and Reported Cases - A Systematic Review Journal of Plastic Reconstructive and Aesthetic Surgery · 2020
    8. The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism Journal of The American Academy of Dermatology · 2020
    9. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia BioMed Research International · 2020
    10. A Small Dose of Botulinum Toxin A Is Effective for Treating Androgenetic Alopecia in Chinese Patients Dermatologic Therapy · 2018
    11. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    12. A Pilot Study to Evaluate Effectiveness of Botulinum Toxin in Treatment of Androgenetic Alopecia in Males Journal of Cutaneous and Aesthetic Surgery · 2017
    13. Frontal Alopecia After Repeated Botulinum Toxin Type A Injections for Forehead Wrinkles: An Underestimated Entity? Skin appendage disorders · 2016
    14. Treatment Effects of Intradermal Botulinum Toxin Type A Injection on Alopecia Areata Dermatologic surgery · 2010
    15. Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study Plastic and Reconstructive Surgery · 2010
    16. Cephalalgic Alopecia Areata: A Case Study Cephalalgia · 2006
    17. Madarosis and Facial Alopecia Presumed Secondary to Botulinum A Toxin Injections Optometry and vision science · 2005
    18. Photographic Documentation of Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996