Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen

July 2012 in “ PLOS ONE ”

Huimin Hu, Shou-bing Zhang, Xiaohua Lei, Zhili Deng, Wei Guo, Zhifang Qiu, Shuang Liu, Xinyue Wang, He Zhang, Enkui Duan

estrogen catagen phase telogen phase hair growth cycle apoptosis precortex cells TGF β2 BMP4 anagen transition hair follicle stem cell niche nonscarring alopecia hair loss hair follicle

Studysummary This study found that estrogen can cause reversible suppression of the hair cycle by inducing premature catagen and maintaining the telogen phase without damaging the hair follicle stem cell niche or the signature gene expressions of dermal papilla cells.

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