Rs4541843 G > A Variant Near miR-182 Is Associated With Susceptibility, Severity, and Increased hsa-miR-182-5p Expression in Alopecia Areata

    June 2026 in “ Archives of Dermatological Research ”
    Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Salem Saleh Bahaj … Lina Mohammed Atef
    Studysummary In this study, the rs4541843 G > A variant was found to be significantly associated with increased risk and severity of alopecia areata, as well as elevated expression of hsa-miR-182-5p, suggesting their potential as molecular markers for diagnosis and severity assessment.
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    2. MiR-200c-3p as a Novel Genetic Marker and Therapeutic Tool for Alopecia Areata Skin Research and Technology · 2024
    3. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    4. Progressive Expression of PPARGC1α Is Associated with Hair Miniaturization in Androgenetic Alopecia Scientific Reports · 2019
    5. The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments Journal of Dermatological Science · 2015
    6. Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing Seminars in Cutaneous Medicine and Surgery · 2012
    7. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010