Synergistic Effect of Microneedle-Delivered Extracellular Matrix Compound and Radiofrequency on Rejuvenation of Periorbital Wrinkles

    July 2022 in “ Frontiers in Medicine ”
    Haiyan Cheng, Ruina Zhang, Fenglin Zhuo
    Studysummary In this study, the combination of ECM-C with microneedle and radiofrequency treatments improved periorbital wrinkles, skin elasticity, and thickness more effectively than ECM-C with microneedles alone, but subjective evaluations showed no significant differences.
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    Research cited in this study 6

    1. Update in Minimally Invasive Periorbital Rejuvenation with a Focus on Platelet-Rich Plasma: A Narrative Review Journal of cosmetic dermatology · 2020
    2. Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair Facial Plastic Surgery Clinics of North America · 2018
    3. Microneedling: Current Status and Systematic Literature Review Journal of Plastic Reconstructive and Aesthetic Surgery · 2017
    4. Microneedling Dilates the Follicular Infundibulum and Increases Transfollicular Absorption of Liposomal Sepia Melanin Clinical, Cosmetic and Investigational Dermatology · 2015
    5. Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy Indian Journal of Dermatology · 2015
    6. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013