Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates

May 2023 in “ European journal of pharmaceutical sciences ”

Yin-Ku Lin, Chien‐Yu Hsiao, Abdullah Alshetaili, Ibrahim A. Aljuffali, Enli Chen, Jia‐You Fang

lipid-based nanoformulations niosomes cutaneous targeting skin-targeted drug delivery skin deposition systemic absorption hair follicle uptake antioxidant ability phospholipid content inflammatory skin diseases alopecia acne drug solubility follicular uptake skin irritation skin diseases hair loss

Studysummary This study found that niosomes significantly enhanced the skin deposition of retinoic acid while reducing its permeation, outperforming other tested nanoformulations.

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