Comparative Efficacy Evaluation of Alopecia Areata Management with Janus Kinase Inhibitors in Children: Retrospective Cohort Study

    December 2025 in “ Педиатрическая фармакология ”
    Alexander I. Materikin, Vladislav V. Ivanchikov, Anastasia D. Kuzminova
    Studysummary In this pediatric retrospective study, tofacitinib (a Janus kinase inhibitor) improved the severity of alopecia and quality of life more effectively than traditional treatment methods, with significant reductions in alopecia severity score and dermatology life quality index over 16 weeks.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on pedpharma.ru →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Long-Term Safety and Efficacy of Ritlecitinib in Adults and Adolescents with Alopecia Areata and at Least 25% Scalp Hair Loss: Results from the ALLEGRO-LT Phase 3, Open-Label Study Journal of the European Academy of Dermatology and Venereology · 2025
    2. Modern Management Approaches for Alopecia Areata Вопросы современной педиатрии · 2025
    3. British Association of Dermatologists Living Guideline for Managing People with Alopecia Areata 2024 British Journal of Dermatology · 2024
    4. Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions Frontiers in immunology · 2023
    5. Treatments for Alopecia Areata: A Network Meta-Analysis The Cochrane library · 2023
    6. Treatment Patterns for Alopecia Areata in the US JAMA Dermatology · 2023
    7. Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials American Journal of Clinical Dermatology · 2023
    8. The National Pediatric Alopecia Areata Registry in Russia: An Overview Journal of the American Academy of Dermatology · 2022
    9. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    10. Brazilian Experience of Treating Alopecia Universalis with Novel Antirheumatic Therapy Tofacitinib: A Case Series Rheumatology and Therapy · 2017
    11. Combination Therapy with Zinc Gluconate and PUVA for Alopecia Areata Totalis: An Adjunctive but Crucial Role of Zinc Supplementation Dermatologic therapy · 2015
    12. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    13. Current Treatment of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    14. The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians International Journal of Dermatology · 2002
    15. Profile of Alopecia Areata: A Questionnaire Analysis of Patients and Families International Journal of Dermatology · 1992