Eucommia Ulmoides Bark Extract Attenuates Oxidative Damage and H2O2-Induced Hair Follicle Suppression in Cellular and Mouse Models

    August 2026 in “ Molecules ”
    Xiaojin Liu, SHUYUE CHEN, Yanyan Zhang … Yefan Gu
    Studysummary This study found that Eucommia ulmoides bark extract shows potential antioxidant and hair follicle-support properties in vitro and in vivo, but further validation is needed to confirm these effects.
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    Research cited in this study 8

    1. Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells Clinical, Cosmetic and Investigational Dermatology · 2021
    2. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    3. Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates General and Comparative Endocrinology · 2020
    4. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017
    5. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    6. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    7. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    8. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001