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    GlossaryHair Follicle Miniaturization (hair follicle regression)

    hair follicles shrink, producing thinner and shorter hair strands

    Hair Follicle Miniaturization is a process where hair follicles gradually shrink, producing thinner and shorter hair strands over time. This phenomenon is commonly associated with androgenetic alopecia (pattern baldness) and can eventually lead to the cessation of hair growth in the affected follicles.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

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      community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

      in Research/Science  5 upvotes 1 year ago
      Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 2 months ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  55 upvotes 7 months ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community The mechanism of androgenic alopecia

      in Research/Science  31 upvotes 3 weeks ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community why are beard gains on min usually permanent?

      in Minoxidil  43 upvotes 1 month ago
      Beard gains from minoxidil are usually permanent due to facial hair follicles' lower sensitivity to DHT. Scalp hair requires ongoing DHT suppression with treatments like finasteride, dutasteride, and RU58841 to maintain gains after stopping minoxidil.