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    Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria

    Iris E. Stoffers, Vries Martine de, Sabine Hannema
    Studysummary In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.
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    Research cited in this study 3

    1. Transgender Adolescents and Acne: A Case Series Pediatric Dermatology · 2018
    2. Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology & Metabolism · 2017
    3. Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men The Journal of Sexual Medicine · 2013