Canine Epidermal Neural Crest Stem Cells: Characterization and Potential as Therapy Candidate for a Large Animal Model of Spinal Cord Injury

    January 2014 in “ Stem Cells Translational Medicine ”
    Barbara Gericota, Joseph S. Anderson, Gaela Mitchell … Maya Sieber‐Blum
    Studysummary This study reports that epidermal neural crest stem cells from dogs (cEPI-NCSC) can generate neural crest derivatives and may offer a new cell-based therapy for canine spinal cord injury, with potential as a model for human treatments.
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    Research cited in this study 7

    1. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC): Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011
    2. Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    3. Hair Loss Disorders in Domestic Animals Veterinary dermatology · 2009
    4. Canine Hair-Follicle Keratinocytes Enriched With Bulge Cells Have the Highly Proliferative Characteristic of Stem Cells Veterinary Dermatology · 2009
    5. Hair Loss Disorders in Domestic Animals Wiley-Blackwell eBooks · 2009
    6. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    7. Beauty Is Skin Deep: The Fascinating Biology of the Epidermis and Its Appendages PubMed · 2000