A Retrospective Analysis of Clinical and Dermoscopic Features of Male Patients with Androgenic Alopecia Before and After Treatment

January 2013 in “ Journal of Clinical Dermatology ”

Liu Shui-fen

androgenic alopecia finasteride minoxidil hair diameter diversity dermoscopy AGA Propecia Rogaine HDD

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Frontline, gold standard treatment for combatting androgenic alopecia

An essential vasodilator with some anti-androgenic effects

Studysummary This study observed that a combination of oral finasteride and topical minoxidil was effective in treating androgenic alopecia in males, with a treatment duration of at least three months being necessary for effectiveness.

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The study retrospectively analyzed 576 male patients with androgenic alopecia (AGA) to assess clinical and dermoscopic features and treatment efficacy. Most patients were young to middle-aged with mild to moderate hair loss, and 61.3% had a family history of AGA. Dermoscopic examination revealed that 87.5% of AGA patients had more than 20% hair diameter diversity (HDD), a significant diagnostic criterion, compared to only 3.4% of normal controls. The combination of oral finasteride and topical 5% minoxidil showed a total effective rate of 75.2%, with effectiveness increasing with treatment duration, particularly after 3 months. Dermoscopy proved valuable for early diagnosis and treatment evaluation.

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