Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments

    August 2024 in “ Journal of Investigative Dermatology ”
    Cristina Quílez, Luís B. Bebiano, Eleri Jones … Diego Velasco
    Studysummary In vitro skin models are improving but still need more innovation to fully replicate human skin.
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    Research cited in this study 19

    1. Mechanical Engineering of Hair Follicle Regeneration by In Situ Bioprinting Biomaterials advances · 2022
    2. Bioprinting of Hair Follicle Germs for Hair Regenerative Medicine Acta biomaterialia · 2022
    3. Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis Frontiers in oncology · 2022
    4. Generation And Characterization Of Hair-Bearing Skin Organoids From Human Pluripotent Stem Cells Nature Protocols · 2022
    5. A Perfusable Vascularized Full-Thickness Skin Model for Potential Topical and Systemic Applications Biofabrication · 2021
    6. Design of In Vitro Hair Follicles for Different Applications in the Treatment of Alopecia: A Review Biomedicines · 2021
    7. Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis Biomedicines · 2020
    8. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    9. Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach Nature Communications · 2018
    10. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    11. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    12. Skin And Hair On-A-Chip: In Vitro Skin Models Versus Ex Vivo Tissue Maintenance With Dynamic Perfusion Lab on a Chip · 2013
    13. Towards Expansion of Human Hair Follicle Stem Cells In Vitro Cell Proliferation · 2011
    14. The Cell Biology of Human Hair Follicle Pigmentation Pigment cell & melanoma research · 2010
    15. Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System Methods in molecular biology · 2010
    16. Hair Matrix Germinative Epidermal Cells Confer Follicle-Inducing Capabilities on Dermal Sheath and High Passage Papilla Cells Development · 1996
    17. Keratin 19 as a Biochemical Marker of Skin Stem Cells In Vivo and In Vitro: Localization and Variation with Age and Culture Stage Journal of Cell Science · 1996
    18. Human Hair Growth In Vitro Journal of Cell Science · 1990
    19. Rat Hair Follicle Dermal Papillae Have an Extracellular Matrix Containing Basement Membrane Components Journal of Investigative Dermatology · 1986