Therapeutic Effect of Finasteride Through Its Antiandrogenic and Antioxidant Role in a Propionic Acid-Induced Autism Model: Demonstrated by Behavioral Tests, Histological Findings and MR Spectroscopy

    April 2022 in “ Neuroscience Letters ”
    Ibrahim Halil Sever, Bahattin Özkul, M F Bozkurt, Oytun Erbaş
    Studysummary In this animal study, finasteride significantly improved autism-like symptoms in rats by reversing biochemical markers and enhancing behaviors, potentially due to its antioxidant and anti-androgen effects.
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    Research cited in this study 3

    1. Physiological and Histological Study of the Effect of Finasteride Drug (Prostacare) on the Fertility of Albino Male Rats Research Journal of Pharmacy and Technology · 2018
    2. Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats Journal of Pharmacology and Experimental Therapeutics · 2011
    3. Androgenic Activity in Autism ˜The œAmerican journal of psychiatry · 1997

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    1. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992