Dupilumab: A Potential Option for Young Children With Alopecia Areata and Atopic Features

    January 2026 in “ Dermatologic Therapy ”
    Ying Gu, Bin Zhang
    Studysummary In this retrospective study, dupilumab treatment in young children with alopecia areata and atopic features was linked to full hair regrowth without serious adverse events, though findings from this small cohort should be interpreted cautiously.
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    Research cited in this study 11

    1. Immune Therapies for Alopecia Areata: Evidence and New Perspectives Expert Review of Clinical Immunology · 2025
    2. Dupilumab Induces Hair Regrowth in Pediatric Alopecia Areata: A Real-World, Single-Center Observational Study Archives of Dermatological Research · 2024
    3. Dupilumab for the Treatment of Alopecia Areata in Pediatric Patients with Atopic Dermatitis: A Scoping Review Pediatric Dermatology · 2024
    4. Dupilumab Therapy for Alopecia Areata: A Case Series and Review of the Literature Journal of Dermatological Treatment · 2024
    5. European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    6. Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-Centre Real-World Retrospective Study Acta dermato-venereologica · 2023
    7. Allergen Desensitization Reduces the Severity of Relapsed Alopecia Areata in Dust-Mite Allergic Patients Experimental Dermatology · 2023
    8. Dupilumab for the Treatment of Alopecia Areata in Children with Atopic Dermatitis JAAD case reports · 2021
    9. Dupilumab Therapy for Alopecia Areata in Pediatric Patients with Concomitant Atopic Dermatitis Journal of the American Academy of Dermatology · 2021
    10. The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm Advances in Therapy · 2017
    11. Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2015