In Vitro Differentiation of Hair Follicle Stem Cells Into Keratinocytes by Simvastatin

    October 2019 in “ Iranian Biomedical Journal ”
    Azar Babakhani, Paria Hashemi, Javad Mohajer Ansari … Malihe Nobakht
    Studysummary This study found that a 5 µM concentration of simvastatin significantly increased the differentiation of hair follicle stem cells into keratinocytes in vitro.
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    Research cited in this study 9

    1. Epidermal Growth Factor Promotes Mesenchymal Stem Cell-Mediated Wound Healing and Hair Follicle Regeneration PubMed · 2017
    2. Culture and Characterization of Rat Hair Follicle Stem Cells 2016
    3. Culture and Characterization of Rat Hair Follicle Stem Cells Cytotechnology · 2014
    4. Differentiation of Human Hair Follicle Stem Cells Into Endothelial Cells Induced by Vascular Endothelial and Basic Fibroblast Growth Factors Molecular Medicine Reports · 2013
    5. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013
    6. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012
    7. Nestin-Positive Hair Follicle Pluripotent Stem Cells Can Promote Regeneration of Impinged Peripheral Nerve Injury The Journal of Dermatology · 2011
    8. The Advantages of Hair Follicle Pluripotent Stem Cells Over Embryonic Stem Cells and Induced Pluripotent Stem Cells for Regenerative Medicine Journal of Dermatological Science · 2010
    9. Human Hair Follicle Pluripotent Stem Cells Promote Regeneration of Peripheral Nerve Injury: An Advantageous Alternative to ES and iPS Cells Journal of Cellular Biochemistry · 2009