Optimization of Culture Conditions for Expansion of Human Epidermal Stem Cells

May 2026 in “ Journal of Health and Allied Sciences NU ”

Vinutha Eshwara Swamy, Nikhil Shetty, Veena Shetty, Tonita Mariola Noronha, Jayaprakasha Shetty, Mohana Kumar Basavarajappa

human epidermal stem cells EpSCs MEM-α FBS EpiLife media KGF EGF HKGS p63 KRT5 growth factors clonogenic potential skin regenerative medicine fetal bovine serum keratinocyte growth factor epidermal growth factor human keratinocyte growth supplement

Studysummary This study concluded that human epidermal stem cells cultured in MEM-α and EpiLife media with growth factors show high proliferation potential and plasticity, suggesting potential use in skin regenerative medicine.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on jhas-nu.in →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research Epidermal Stem Cells: Skin Surveillance And Clinical Perspective

19 citations , August 2024 in “Journal of Translational Medicine”

This review explores recent advancements in understanding how various physiological and psychological factors, such as stress and aging, influence epidermal stem cell populations, highlighting their importance in immune-related skin disorders and potential for clinical applications.

research P63: A Crucial Player In Epithelial Stemness Regulation

54 citations , October 2023 in “Oncogene”

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

research Progress in Studies of Epidermal Stem Cells and Their Application in Skin Tissue Engineering

44 citations , July 2020 in “Stem Cell Research & Therapy”

This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.

research Epidermal Stem Cells in Wound Healing and Their Clinical Applications

129 citations , July 2019 in “Stem Cell Research & Therapy”

This review examines the role of epidermal stem cells in wound healing, discussing their characteristics and mechanisms, but does not report new clinical results.

research Keratin K15 as a Biomarker of Epidermal Stem Cells

85 citations , September 2013 in “International Journal of Molecular Sciences”

This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.

research Beyond Wavy Hairs: The Role of EGFR in Skin and Hair Biology

160 citations , June 2008 in “American Journal Of Pathology”

This review discusses the effects of the epidermal growth factor receptor system on skin biology and pathology, relying on animal models to analyze roles in cellular processes, wound healing, and tumorigenesis, but reports no new results.