Targeting Lymphoid-Derived IL-17 Signaling to Delay Skin Aging

    June 2023 in “ Nature Aging ”
    Paloma Solá, Elisabetta Mereu, Júlia Bonjoch … Salvador Aznar Benitah
    Studysummary This study observed that in aged mouse skin, there was an increase in IL-17-expressing T helper cells, γδ T cells, and innate lymphoid cells, and blocking IL-17 signaling reduced skin inflammation and delayed age-related changes, suggesting it as a potential target to mitigate skin aging.
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    Research cited in this study 10

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    5. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    6. Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche Nature Reviews Molecular Cell Biology · 2013
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