Epidermal Structure Created by Canine Hair Follicle Keratinocytes Enriched with Bulge Cells in a Three-Dimensional Skin Equivalent Model In Vitro: Implications for Regenerative Therapy of Canine Epidermis

    January 2013 in “ Veterinary dermatology ”
    Tetsuro Kobayashi, Kaoru Enomoto, Yu Hsuan Wang … Koji Nishifuji
    Studysummary This study found that a bulge stem cell-enriched population from canine hair follicles successfully formed interfollicular epidermis in vitro within two weeks, suggesting potential for regenerative canine skin therapies.
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    Research cited in this study 7

    1. Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    2. Canine Hair-Follicle Keratinocytes Enriched With Bulge Cells Have the Highly Proliferative Characteristic of Stem Cells Veterinary Dermatology · 2009
    3. Exploring the Role of Stem Cells in Cutaneous Wound Healing Experimental Dermatology · 2009
    4. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    5. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    6. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    7. Artificial Skin for Wound Healing Clinics in Dermatology · 1994

    Related research 4

    1. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    2. Keratins of the Human Hair Follicle International review of cytology · 2005
    3. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    4. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003