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GlossaryDesmoglein

protein aiding cell adhesion in skin and tissues

Desmoglein is a type of protein found in the skin and other tissues that helps cells stick together, forming strong connections called desmosomes. These proteins are crucial for maintaining the structural integrity of tissues, and their dysfunction can lead to skin disorders and diseases such as pemphigus, where the skin becomes fragile and blisters easily.

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research Desmogleins: Hair Perspective

4 citations , January 2013 in “International Journal of Trichology”

Desmogleins are crucial for hair structure and growth.

research Pemphigus Vulgaris IgG and Methylprednisolone Exhibit Reciprocal Effects on Keratinocytes

99 citations , January 2004 in “Journal of Biological Chemistry”

Methylprednisolone helps skin cells stick together better in pemphigus vulgaris.

research Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus

1 citations , September 2019 in “Journal of Investigative Dermatology”

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

research Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus

1 citations , August 2019

Anti-Desmocollin 3 antibodies can cause atypical pemphigus symptoms.

research Epidermal Structure Created by Canine Hair Follicle Keratinocytes Enriched with Bulge Cells in a Three-Dimensional Skin Equivalent Model In Vitro: Implications for Regenerative Therapy of Canine Epidermis

11 citations , January 2013 in “Veterinary dermatology”

Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.

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