Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer
September 2022
in “
Frontiers in pharmacology
”
Epimedium brevicornum Maxim. Epimedii Folium extract EFE melanin synthesis melanosome biogenesis melanosome transfer melanocytes tyrosinase activity tyrosinase protein expression MAPK/ERK1/2 signaling pathway epimedin B hypopigmentation disorders Epimedium Epimedium extract melanin production melanosome formation melanosome movement skin cells tyrosinase enzyme tyrosinase protein MAPK/ERK pathway EB skin pigmentation disorders
Studysummary In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.
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