Safety and Efficacy of ALRV5XR in Women with Androgenetic Alopecia or Telogen Effluvium: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial

    June 2021 in “ EClinicalMedicine ”
    Peter D. Feldman, Klaus M. Fiebig, Charles Piwko … Jaime Guevara-Aguirre
    Studysummary In this study, ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported.
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    Research cited in this study 22

    1. Telogen Effluvium Associated with COVID-19 Infection Dermatologic Therapy · 2021
    2. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    3. Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options Expert Opinion on Therapeutic Targets · 2019
    4. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    5. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    6. Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use Dermatology practical & conceptual · 2017
    7. SALT II: A New Take on the Severity of Alopecia Tool for Determining Percentage Scalp Hair Loss Journal of The American Academy of Dermatology · 2016
    8. Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment Fitoterapia · 2016
    9. Advances in Understanding Hair Growth F1000Research · 2016
    10. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    11. Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia Dermatologic Therapy · 2014
    12. Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles Journal of Dermatological Science · 2013
    13. Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease JAMA Dermatology · 2013
    14. What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women British Journal of Dermatology · 2012
    15. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    16. Follicular Miniaturization in Female Pattern Hair Loss: Clinicopathological Correlations British Journal of Dermatology · 2006
    17. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    18. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    19. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    20. Incidence of Female Androgenetic Alopecia (Female Pattern Alopecia) Dermatologic Surgery · 2001
    21. Treatment of Hair Loss The New England Journal of Medicine · 1999
    22. Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects Journal of The American Academy of Dermatology · 1993

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    4. Hair Disorders Oxford University Press eBooks · 2018
    5. Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial Evidence-based Complementary and Alternative Medicine · 2014