Histologic Study of the Regeneration Process of Human Hair Follicles Grafted onto SCID Mice after Bulb Amputation

    November 2001 in “ Journal of Investigative Dermatology Symposium Proceedings ”
    Tsuyoshi Hashimoto, Tatsuo Kazama, Masaaki Ito … Yoshito Ueyama
    Studysummary This study observed that human hair follicles with a completely destroyed bulb can regenerate after being grafted onto immunodeficient mice, entering a shortened dystrophic telogen followed by anagen phase.
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    Research cited in this study 10

    1. Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice Journal of Investigative Dermatology · 2000
    2. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000
    3. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    4. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    5. Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse Journal of Investigative Dermatology · 1996
    6. The Upper Dermal Sheath Has Potential to Regenerate Hair in Rat Follicular Epidermis Differentiation · 1996
    7. Growth Factor and Growth Factor Receptor Localization in the Hair Follicle Bulge and Associated Tissue in Human Fetus Journal of Investigative Dermatology · 1996
    8. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995
    9. Specific Receptor Detection by a Functional Keratinocyte Growth Factor-Immunoglobulin Chimera ˜The œjournal of cell biology/˜The œJournal of cell biology · 1995
    10. Epithelial-Stromal Interactions in Basal Cell Cancer: The PDGF System Journal of Investigative Dermatology · 1994

    Related research 6

    1. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Dermal Sheath Cells Contribute to Postnatal Hair Follicle Growth and Cycling Journal of Dermatological Science · 2016
    4. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    6. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996