March 20269
Emerging pharmacotherapies for pattern hair loss found exosomes, PRP, peptides and pyrilutamide show early potential, though data remain heterogeneous and long-term trials are still needed. Microneedle delivery for hair regrowth was found to enhance therapeutic modalities, with clinical trials lagging far behind basic research. In 261 bariatric patients, postoperative hair loss after bypass versus sleeve peaked at three months and eased by six, with low iron and female sex predicting it. Chemotherapy-induced alopecia in breast cancer caused severe loss in over 70% on anthracycline/taxane regimens, with persistent loss up to 67% on doxorubicin.
- Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy In 261 bariatric patients, hair loss peaked at 3 months and eased by 6; low iron and female sex predicted it, and it proved reversible with supplementation.
- Emerging pharmacotherapies and regenerative solutions for promoting hair growth for androgenetic alopecia A review finds exosomes, PRP, peptides, and pyrilutamide show early promise for AGA, but heterogeneous data mean rigorous long-term trials are still needed.
- Microneedle technology integrated with diverse therapeutic modalities for hair regrowth in alopecia A review finds microneedle delivery can enhance hair-regrowth therapies, but clinical trials lag far behind basic research.
- Chemotherapy-Induced Alopecia in Breast Cancer Patients: Treatment-Specific Incidence and Risk of Persistent Hair Loss A scoping review found anthracycline/taxane regimens cause severe alopecia in over 70%, with persistent loss up to 67% on doxorubicin — higher than historically reported and still underreported in trials.
- Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance A review proposes a framework classifying autoimmune and scarring alopecias by where follicular immune privilege collapses.
- Trichoscopic Evaluation of the Effectiveness of Topical Stemoxydine for Hair Restoration in Androgenetic Alopecia: A Prospective Pre–Post Single‐Arm Exploratory Study In a 35-patient single-arm study, topical stemoxydine increased hair density and diameter over 3 months, with mild redness the commonest side effect.
- Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights A review links AGA scalps to Cutibacterium acnes enrichment and sebum shifts that may fuel inflammation and follicle miniaturization.
- Prescribing Habits for Androgenetic Alopecia Among Dermatologists in Spain in 2024: A Cross-Sectional Study A survey of 202 Spanish dermatologists found oral minoxidil is now the top AGA prescription, and dutasteride has overtaken finasteride in men.
- Folliculin: A surprising molecular brake in the human hair follicle folliculin is identified as a surprising molecular brake in the human hair follicle.