July 202132
PRP as a graft holding solution was reported to speed recovery and improve hair density after hair transplant in a randomized trial. A review of finasteride found 1 mg, 5 mg and topical formulations similarly effective, with sexual side effects common and depression added to the FDA label after reports of persistent symptoms and suicide risk. A triangular donor strip tip gave better hair alignment than elliptical excision. De-epithelializing FUE grafts improved immediate appearance without affecting graft survival. Aerobic exercise or longer sessions were associated with delayed pattern hair loss progression. A meta-analysis of quality of life found AGA moderately impairs quality of life and emotions but showed no association with depression. A ceria nanozyme microneedle patch regrew hair faster than minoxidil in mice.
- Randomized control trial to study the efficacy and safety of platelet-rich plasma as intraoperative holding solution in hair restoration surgery: A pilot study In a 20-patient randomized trial, storing grafts in PRP sped recovery and improved hair density six months after hair transplant.
- Finasteride for hair loss: a review Review found 1 mg, 5 mg and topical finasteride similarly effective; sexual side effects are common, depression was added to the FDA label after reports of persistent symptoms and suicide risk, so patients should be counselled on short- and long-term effects.
- New Donor Excision Design for Better Hair Alignment in Hair Restoration Surgery A triangular flag-shaped donor strip tip gave better hair alignment than elliptical design in 157 hair transplant patients.
- Relationship between the exercise and severity of androgenic alopecia. A survey of AGA patients found aerobic exercise or sessions over 60 minutes associated with delayed progression and improvement.
- Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment A ceria nanozyme microneedle patch regrew hair faster than minoxidil at lower dosing frequency in AGA mice without skin damage.
- Health-Related Quality of Life, Depression, and Self-esteem in Patients With Androgenetic Alopecia Meta-analysis of 41 studies found AGA moderately impairs quality of life and emotions but is not associated with depression.
- Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice Cholesterol-modified siRNAs against FGF5 or FGF18, injected or topical, prolonged anagen and promoted hair growth in mice.
- Effect of De-epithelialization on Graft Survival Rate After Follicular Unit Extraction A randomized study of 64 FUE patients found de-epithelializing grafts improved immediate appearance without affecting graft survival.
- Glutamic acid promotes hair growth in mice Topical glutamic acid promoted hair growth and keratinocyte proliferation in mice and human cell cultures.
- Impact of lisinopril on cardiometabolic risk factors in men with hypertension and early-onset androgenetic alopecia Lisinopril's cardiometabolic benefits were blunted in hypertensive young men with early-onset pattern baldness.
- Morus alba Root Extract Induces the Anagen Phase in the Human Hair Follicle Dermal Papilla Cells Morus alba root extract activated β-catenin and induced the anagen phase in human hair follicle dermal papilla cells.
- Evaluation of serum G protein-coupled estrogen receptor 1 (GPER-1) levels in patients with androgenetic alopecia Serum estrogen receptor GPER-1 levels were elevated in AGA patients versus controls regardless of sex.
- Alopecia Areata Treatment Patterns, Healthcare Resource Utilization, and Comorbidities in the US Population Using Insurance Claims US claims data from 68,121 alopecia areata patients showed high comorbidity burden; most treated patients received topical or oral steroids.
- The role of CTHRC1 in hair follicle regenerative capacity restored by plantar dermis homogenate Plantar dermis homogenate restored hair follicle spheroid regenerative capacity via CTHRC1 in lab and mouse experiments.
- Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata Alopecia areata patients had elevated serum IL-2, IL-4, and IL-15 that decreased with tofacitinib but didn't correlate with disease severity.
- An Approach to Hair Loss in Pediatric Primary Care A review summarizes evaluation and treatment approaches for pediatric hair loss for primary care practitioners.
- Defining a Role for G-Protein Coupled Receptor/cAMP/CRE-Binding Protein Signaling in Hair Follicle Stem Cell Activation G-protein coupled receptor/cAMP/CREB signaling through adrenergic receptors regulates hair follicle stem cell activation and hair cycle initiation.
- Use of facial care products and frontal fibrosing alopecia: Coincidence or true association? Higher moisturizer and sunscreen use in Asian women with frontal fibrosing alopecia or pattern hair loss appears linked to appearance concerns, not disease mechanism.
- Transcription Factor DLX5 Promotes Hair Follicle Stem Cell Differentiation by Regulating the c-MYC/microRNA-29c-3p/NSD1 Axis The transcription factor DLX5 promotes hair follicle stem cell differentiation by regulating the c-MYC/miR-29c-3p/NSD1 axis.
- Evaluation of dry eye and Meibomian gland dysfunction in female androgenetic alopecia patients Women with androgenetic alopecia had worse dry-eye tests and Meibomian gland dysfunction than controls in a small observational study.
- Topical dapsone for folliculitis decalvans: A retrospective cohort study A retrospective cohort study examines topical dapsone for folliculitis decalvans.
- Association of resilience and perceived stress in patients with alopecia areata: A cross-sectional study a cross-sectional study of resilience and perceived stress in alopecia areata patients.
- Dermatologic Care of Hair in Transgender Patients: A Systematic Review of Literature A systematic review covers hair changes and treatment options for transgender patients on hormonal therapy.
- The epidemiology of alopecia areata: a population‐based cohort study in UK primary care* Alopecia areata incidence in UK primary care was 0.26 per 1000 person-years, with higher rates in Asian ethnicity and deprived urban populations.
- Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Centipeda minima extract stimulated human dermal papilla cell proliferation via Wnt/beta-catenin, ERK and JNK pathways in vitro.
- Reversal of alopecia areata, osteoporosis follow treatment with activation of Tgr5 in mice Tgr5 activation improved alopecia areata and osteoporosis in mice by down-regulating the JAK1-STAT3 signaling pathway.
- Impact of Laboratory Work Up and Supplementation on Alopecia Patients: A Single-Center Retrospective Chart Review. In a retrospective review of 131 alopecia patients, vitamin supplementation did not improve hair density or diameter.
- <i>Lactobacillus paracasei</i> HY7015 Promotes Hair Growth in a Telogenic Mouse Model Oral Lactobacillus paracasei HY7015 promoted hair growth in mice by stimulating dermal papilla cell proliferation and growth factor secretion.
- Measuring Patient Quality of Life Following Treatment for Alopecia A review of questionnaires used to measure quality of life in alopecia patients, discussing applications and limitations.
- Systematic review of finasteride effect in women with hirsutism. a systematic review of finasteride for hirsutism in women.
- Significant hair regrowth in a Middle Eastern woman with central centrifugal cicatricial alopecia
- Head and Neck Restoration in Scar Alopecia: Hair Transplantation in Scalp, Eyebrows, Beard and Mustache