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    Did you mean Tyrosine Kinase?
    Glossary Tyrosine Kinase

    enzyme that transfers phosphate groups to tyrosine on proteins

    Tyrosine Kinase (TK) is an enzyme that functions by transferring a phosphate group from ATP to a specific amino acid called tyrosine on a protein. This process, known as phosphorylation, is crucial for regulating various cellular activities, including cell division, growth, and signaling pathways. Dysregulation of tyrosine kinases can lead to diseases such as cancer, making them important targets for certain therapeutic drugs.

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    1. Repigmentation of leukoderma in a piebald patient associated with a novel c-KIT gene mutation, G592E, of the tyrosine kinase domain Journal of Dermatological Science · 2011 · 6 citations
    2. Clinical Manifestations of Hyperandrogenism and Ovulatory Dysfunction Are Not Associated with His1058 C/T SNP (rs1799817) Polymorphism of Insulin Receptor Gene Tyrosine Kinase Domain in Kashmiri Women with PCOS International Journal of Endocrinology · 2021 · 6 citations
    3. 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis Journal of Investigative Dermatology · 2017
    4. Epidermal growth factor receptor mutant T790M-L858R-V948R inhibitor from Calophyllum inophyllum L. leaf as potential non-small cell lung cancer drugs Journal of pharmacy & pharmacognosy research · 2024
    5. Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-small Cell Lung Cancer Journal of thoracic oncology · 2006 · 12 citations
    6. A Case of Inflammatory Nonscarring Alopecia Associated With the Tyrosine Kinase Inhibitor Nilotinib JAMA Dermatology · 2013 · 16 citations
    7. Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System Scientific Reports · 2020 · 58 citations
    8. 700 Tyrosine kinase 2 inhibition rescues hair follicles from IL-12–mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model Journal of Investigative Dermatology · 2022
    9. Keratosis Pilaris-like Eruption during Treatment of Chronic Myeloid Leukemia with Tyrosine Kinase Inhibitors: Literature Review and Report of a Case Related to Imatinib Journal of clinical medicine · 2023
    10. Characterisation, genomic organisation, expression and function of the mEphA1 receptor Tyrosine Kinase 2007
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