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5 / 7 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Stem Cell Factor
learn Metformin
diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
Research
5 / 1000+ results
research Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy
Methylation in specific gene region causes finasteride resistance in some BPH patients.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Design, Synthesis, and Biological Evaluation of Novel Androst-3,5-Diene-3-Carboxylic Acid Derivatives as Inhibitors of 5α-Reductase Type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research Methylation And Decreased Expression Of 5-Alpha Reductase 2 In Human Prostate Samples: Implications For Resistance To Therapy For BPH
The study investigated the role of 5-alpha reductase type 2 (5-AR2) in resistance to Finasteride therapy for benign prostatic hyperplasia (BPH). In a sample of 21 human prostate tissues, 29% did not express the 5-AR2 protein, and 38% showed methylation in the 5-AR2 promoter region, which correlated with low protein expression. This methylation was linked to resistance to Finasteride, as it inhibits 5-AR2. The study concluded that methylation of the 5-AR2 gene may lead to reduced expression of the protein, explaining why some patients with BPH are resistant to 5-AR2 inhibitors like Finasteride.
research Selective Non-Steroidal Inhibitors of 5α-Reductase Type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
Community Join
5 / 1000+ resultscommunity ghk-cu is potent 5-ar inhibitor?
GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.
community Why don't we all just take 2.5mg dutasteride?
Switching from finasteride and minoxidil to a higher dose of dutasteride for hair loss is debated due to potential side effects. Many suggest starting with lower doses or sticking to finasteride if effective.
community Thoughts on this Article: Post-Finasteride and Neurological Effects
The conversation discusses the effects of finasteride on hair loss and its potential neurological and sexual side effects. Users share personal experiences, with some reporting positive outcomes and others expressing concerns about cognitive function.
community [AMA] 5-Month Progress Report: Dutasteride and Oral Minoxidil Results.
Naepo's 5-month progress report detailing their journey of treating male pattern baldness with dutasteride and oral minoxidil, which has already resulted in an encouraging improvement in hair density. Others have responded with appreciation for the thorough report and asked further questions about Naepo's educational background.
community PSA: Fin/Dut are NON-NEGOTIABLE
Finasteride and dutasteride are essential for stopping hair loss, while natural remedies are ineffective. Minoxidil can be added if needed, but blocking DHT is crucial.