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research Clinical Efficacy of Topical or Oral Soy Supplementation in Dermatology: A Systematic Review

2 citations , June 2023 in “Journal of clinical medicine”

This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.

research Topical minoxidil and dietary supplement for the treatment of chemotherapy-induced alopecia in childhood: a retrospective cohort study

February 2024 in “Scientific Reports”

In this retrospective cohort study, 87.1% of pediatric patients with chemotherapy-induced alopecia experienced clinical improvement after treatment with minoxidil or combination therapy with CYP, with the combination therapy showing greater hair thickness and minimal adverse effects.

research FULL SUPPLEMENT: Emerging Topical Approaches in the Management of Female Pattern Hair Loss

May 2026 in “Journal of Drugs in Dermatology”

New topical treatments and methods can help manage female pattern hair loss.

research Supplementary Material for: Efficacy of Topical Minoxidil for Nail Growth: A Systematic Review

June 2026 in “Figshare”

This systematic review found that topical minoxidil significantly increases nail growth in healthy individuals and patients with nail disorders, showing a promising mean increase in growth rate and clinical response compared to controls, without serious adverse effects reported.

research Supplementary Material for: Efficacy of Topical Minoxidil for Nail Growth: A Systematic Review

June 2026 in “Figshare”

This systematic review found that topical minoxidil may safely enhance nail growth, with significant increases observed in healthy individuals and those with nail disorders, although larger trials are necessary to confirm its long-term efficacy.

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Community Join

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community Starting MV Supplements topical RU+Min with Copper Peptides added.

in Product 5 upvotes 1 year ago

The conversation is about starting a hair loss treatment using a topical solution containing RU58841, Minoxidil, and Copper Peptides. The user plans to test the product and share updates on its effectiveness.

community 16 days. Topical Min 5% once a day • derma roller 0.25mm every day, 1mm once a week • Foligain Trioxidil shampoo (I let it rest for 10 minutes) • mix of supplements

in Progress Pictures 102 upvotes 1 year ago

The conversation is about a user's hair regrowth progress using topical Minoxidil 5%, a derma roller, Foligain Trioxidil shampoo, and various supplements like zinc, selenium, magnesium, B6, B7, saw palmetto, and D3 + K2. The user is seeking finasteride but faces prescription challenges in Italy.

community Using creatine supplement to balance out the side effects of topical finasteride

10 upvotes 4 years ago

Using creatine to balance side effects of topical finasteride is debated, with concerns it may reduce finasteride's effectiveness. Some users consider alternatives like cordyceps mushroom extract, while others question creatine's impact on DHT levels.

community Current regimen: Topical finasteride 0.3% Minoxidil 6% once daily. 5 months. Also just started taking Zinc 20MG daily. Saw Palmetto 450mg daily. Hair, skin & nails supplements (includes a bunch of vitamins essential for hair skin and nails) Was debating on adding oral finasteride. Thoughts?

in Finasteride/Dutasteride 6 upvotes 1 year ago

The user is using a regimen of topical finasteride 0.3% and minoxidil 6% daily, along with zinc, saw palmetto, and hair supplements, but is unsure about the results and considering adding oral finasteride. Other users share mixed experiences with similar treatments, suggesting patience or switching to oral forms.

community Male - 25 y.o - gulfs slowly fading like my father’s - topical minoxidil, soon starting fin + keratine supplement

in Journals / Progress Pictures 214 upvotes 2 years ago

A 25-year-old male is using topical minoxidil and plans to start finasteride and a keratin supplement to combat hair loss. He will document his progress with photos and track any side effects.

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Learn

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learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn Platelet-Rich Plasma

Is Platelet-Rich Plasma more effective when combined with topical treatments or supplements? Small, mostly high-risk-of-bias trials suggest adding PRP to minoxidil may improve hair density; the evidence is low to very low certainty, and no trial has tested PRP with supplements.

learn Melatonin

Hormone that regulates sleep, sold as a supplement

Is melatonin better as a supplement or applied to the scalp? No study has compared oral and topical melatonin head to head. Topical melatonin has one small placebo-controlled pilot trial in 40 women plus a set of mostly uncontrolled studies of a cosmetic solution; oral melatonin has no published hair-loss trial at all.

learn Biotin

Vitamins vs. minoxidil: who wins the battle for hair growth? Topical minoxidil is approved for pattern hair loss and has trial evidence; reviews find that reported benefits of vitamins such as biotin come mainly from people with a deficiency. The FDA warns that biotin supplements can make some blood tests give wrong results.

learn Saw Palmetto

Palm-berry extract taken as a supplement

learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

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