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An essential vasodilator with some anti-androgenic effects, has excellent safety record
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much-hyped research compound targeting prolactin receptor in scalp
learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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Microscopic delivery system that sends growth-promoting signals to hair follicles
learn Estradiol
an estrogen promoting hair regrowth more commonly used in women
Research
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research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Therapeutic Effects of Minoxidil High Extra Combination Therapy in Patients with Androgenetic Alopecia
research Therapeutic Effects of Patchouli (Pogostemon Cablin) Essential Oil in Relieving Eczema Symptoms in Infants and Toddlers: A Literature Review
Patchouli essential oil may help reduce eczema symptoms in infants and toddlers.
research Therapeutic Effects of Topical Cetirizine in the Treatment of Female Pattern Hair Loss: A Randomized Controlled Noninferiority Trial
Cetirizine lotion can effectively treat female pattern hair loss.
research Therapeutic Effects of Growth Factor Cocktail Including Fibroblast Growth Factor 9 in Patients with Pattern Hair Loss
A growth factor cocktail with FGF9 and microneedling effectively increases hair density and diameter in hair loss patients.
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5 / 129 resultscommunity Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Sublingual Minoxidil - Cure to Hairloss?
The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.
community "When comparing 5% minoxidil with 0.60 mm or 1.20 mm needle lengths, Faghihi et al. found that 0.60 mm needle lengths led to significant hair count and diameter increases versus 5% minoxidil, whereas 1.20 mm needle lengths only saw hair count increases versus 5% minoxidil"
Microneedling with 0.6 mm needles combined with 5% minoxidil is more effective for hair count and thickness than minoxidil alone or with 1.2 mm needles. Biweekly microneedling at 0.6 mm depth is recommended for better results in treating androgenetic alopecia.
community Severe Vitamin D deficiency?
The conversation is about severe Vitamin D deficiency and its potential link to hair loss. The user is already using oral finasteride, topical finasteride, and topical minoxidil for aggressive hair loss.