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research Clinical Effectiveness of Two Old Immunosuppressant Drugs, Methotrexate and Azathioprine, in the Treatment of Lichen Planopilaris: A Randomized Clinical Trial

1 citations , January 2024 in “Dermatologic Therapy”

This study found that both methotrexate and azathioprine were equally effective and well-tolerated in improving symptoms of lichen planopilaris over six months, with no significant difference between the two treatments in terms of efficacy.

research Clinical effectiveness of ethinylestradiol-cyproterone acetate and raloxifene combination therapy in polycystic ovary syndrome-associated infertility

January 2025 in “American Journal of Translational Research”

This study reported that the combination of EE-CPA and raloxifene effectively manages PCOS-related infertility, enhancing pregnancy outcomes through improvements in metabolism, sex hormones, ovarian function, and endometrial receptivity, without significantly increasing adverse effects.

Clinical Effectiveness of Finasteride Versus Hydroxychloroquine in the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial

research Clinical effectiveness of finasteride versus hydroxychloroquine in the treatment of frontal fibrosing alopecia: A randomized controlled trial

September 2023 in “Journal of Cosmetic Dermatology”

In this study, both finasteride and hydroxychloroquine were found to be equally effective, safe, and well-tolerated first-line treatments for frontal fibrosing alopecia in female patients, with no significant differences in efficacy between the two therapies over six months.

Substances Declared as Active Ingredients in Topical Anti-Hair Loss Products: A Review of the Evidence for Their Effectiveness in Light of Clinical Studies

research Substances declared as active ingredients in topical anti-hair loss products – a review of the evidence for their effectiveness in light of clinical studies

June 2026 in “Homo Politicus (Academy of Humanities and Economics in Lodz)”

The effectiveness of ingredients in anti-hair loss products varies, and clinical trials are crucial to determine their success.

Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

research Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam

July 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair shedding in Vietnamese patients with androgenetic alopecia, with high patient satisfaction and minimal side effects.

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learn SCUBE3

What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth? No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

learn Redensyl

commercial product with a blend of mostly natural ingredients for hair regrowth

learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

learn Follistatin

Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Tofacitinib

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

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community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 2 years ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community Has anyone here tried Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster?

in Technology 1 upvotes 6 months ago

The conversation discusses the effectiveness of Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster for hair shedding and thinning. The main ingredient, Aminexil, is compared to Minoxidil, and the user seeks real experiences to determine its efficacy.

community Verteporfin Phase 1 Human Clinical Trial In The Works - Research

92 upvotes 1 year ago

Verteporfin is being discussed for its potential to regrow hair and heal scars, possibly aiding hair transplants or replacing them. Some users are skeptical about its effectiveness, while others suggest combining it with microneedling for better results.

community Evidence of DUT shedding in clinical trials?

in Finasteride/Dutasteride 6 upvotes 1 month ago

Switching from finasteride to dutasteride may cause increased hair shedding, which is not well-documented in clinical trials. Some users report success with dutasteride, but experiences vary, and expectations may influence perceptions of effectiveness.

community Han Bio Aims for Phase 1 Clinical Trials in 2027 after successful hair growth in mice

in Research/Science 248 upvotes 1 year ago

Han Bio plans to start Phase 1 clinical trials for a hair growth treatment in 2027 after successful results in mice. Many users express skepticism about the effectiveness of treatments that work on mice but not on humans, and discuss existing treatments like finasteride and minoxidil.

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