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    GlossaryT cell infiltration (T-lymphocyte infiltration)

    movement of T lymphocytes into tissue, often causing inflammation

    T cell infiltration refers to the movement and accumulation of T lymphocytes (a type of white blood cell) into a specific tissue or organ. This process often occurs in response to infection, inflammation, or autoimmune conditions, where T cells target and attack perceived threats, such as pathogens or, in some cases, the body's own cells. In the context of alopecia, T cell infiltration can lead to the immune system attacking hair follicles, resulting in hair loss.

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      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 5 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community Don't know how but this is an accurate depiction

      in Satire  265 upvotes 2 months ago
      The conversation humorously discusses hair loss treatments, including topical finasteride, oral dutasteride, topical minoxidil, RU58841, peppermint oil, and microneedling. It also mentions lifestyle changes like converting to Islam and avoiding smoking, drinking, and partying.