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Glossary Sulfotransferase

enzyme that attaches sulfate groups to other molecules

Sulfotransferase is an enzyme that adds sulfate groups to molecules, a process known as sulfation. This modification can change the function or activity of the target molecules, which often include hormones, drugs, and proteins. In the context of hair biology, sulfotransferases can influence hair growth and health by modifying signaling molecules involved in these processes.

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Research

5 / 415 results

research Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination

83 citations , July 2008 in “Current Opinion in Chemical Biology”

This review discusses the structural and functional advances in understanding sulfotransferases and sulfatases, highlighting new insights into enzyme mechanisms and inactivation by clinically relevant aryl sulfamates, but provides no new experimental results.

research Sulfation of minoxidil by multiple human cytosolic sulfotransferases

59 citations , February 1998 in “Chemico-Biological Interactions”

This study found that at least four different human sulfotransferase activities contribute to the sulfation of minoxidil, complicating predictions of individual responses based on ST levels.

Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?

research Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?

48 citations , July 1996 in “Human & Experimental Toxicology”

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

research Sulfation of minoxidil by human platelet sulfotransferase

39 citations , November 1987 in “Clinica Chimica Acta”

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

research Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1

22 citations , December 2020 in “mSphere”

This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.

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community What Determines Sulfotransferase Enzyme Levels In The Body?

in Minoxidil 7 upvotes 1 year ago

Some people have low sulfotransferase enzyme levels, affecting their response to minoxidil. Lifestyle factors, genetics, and diet, like MSM intake, might influence these enzyme levels.

community Any information on if adapalene also increases sulfotransferase the same way tretinoin does?

in Minoxidil 2 upvotes 9 months ago

The conversation discusses whether adapalene (Differin) increases sulfotransferase like tretinoin does, in the context of combining it with minoxidil for hair treatment. The responses indicate that adapalene does not have the same effect as tretinoin.

community Any update on AB-103? (minoxidil sulfotransferase stimulant)

in Minoxidil 3 upvotes 5 months ago

AB-103, a minoxidil sulfotransferase stimulant, is discussed as a potential hair loss treatment. Users inquire about effective boosters for hair growth.

community I literally can’t find any evidence of sulfotransferase being upregulated by microneedling or retinoids like tretinoin

in Research/Science 4 upvotes 1 year ago

Microneedling and tretinoin may enhance minoxidil absorption for hair loss, but evidence on their effectiveness is limited. Iron supplements and broccoli sprouts are suggested for enzyme activation, but their impact on hair is unclear.

community Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity

in Minoxidil 1 upvotes 1 year ago

Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.

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