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    Glossary Sulfotransferase

    enzyme that attaches sulfate groups to other molecules

    Sulfotransferase is an enzyme that adds sulfate groups to molecules, a process known as sulfation. This modification can change the function or activity of the target molecules, which often include hormones, drugs, and proteins. In the context of hair biology, sulfotransferases can influence hair growth and health by modifying signaling molecules involved in these processes.

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    Research 10 of 350

    1. Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination Current Opinion in Chemical Biology · 2008 · 83 citations
    2. Sulfation of minoxidil by multiple human cytosolic sulfotransferases Chemico-Biological Interactions · 1998 · 59 citations
    3. Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism? Human & Experimental Toxicology · 1996 · 48 citations
    4. Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1 mSphere · 2020 · 22 citations
    5. Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent Dermatologic Therapy · 2018 · 8 citations
    6. Minoxidil Sulfotransferase Enzyme (SULT1A1) genetic variants predicts response to oral minoxidil treatment for female pattern hair loss Journal of The European Academy of Dermatology and Venereology · 2020 · 7 citations
    7. The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity. PubMed · 2019 · 4 citations
    8. Sulfation of minoxidil by human platelet sulfotransferase Clinica Chimica Acta · 1987 · 39 citations
    9. Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia Dermatologic Therapy · 2014 · 20 citations
    10. Oral minoxidil bio‐activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss Journal of The European Academy of Dermatology and Venereology · 2019 · 9 citations
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    Community 10 of 33

    1. Any information on if adapalene also increases sulfotransferase the same way tretinoin does? Reddit · 7 Dec 2025
    2. I literally can’t find any evidence of sulfotransferase being upregulated by microneedling or retinoids like tretinoin Reddit · 18 Aug 2025
    3. Tretinoin vs. micro-needling: what increases sulfotransferase activity more? Reddit · 3 Jul 2025
    4. Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity Reddit · 12 Apr 2025
    5. What Determines Sulfotransferase Enzyme Levels In The Body? Reddit · 16 Dec 2024
    6. Do the more newer gen topical retinoids e.g. tazarotene outperform tretinoin in inducing follicular sulfotransferase activity? Reddit · 29 Jul 2026
    7. Any update on AB-103? (minoxidil sulfotransferase stimulant) Reddit · 29 Mar 2026
    8. Have any topical min NON-responders had success with oral min? Reddit · 3 May 2026
    9. Who won’t respond to minoxidil? (Studies) Reddit · 4 Mar 2026
    10. Could the salicylic acid in my Nioxin shampoo reduce minoxidil effectiveness? Reddit · 25 Feb 2026
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