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research Characterization of Xenobiotic Metabolizing Enzymes of a Reconstructed Human Epidermal Model from Adult Hair Follicles

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations , June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Hutchinson-Gilford Progeria Syndrome - A Brief Introduction

2 citations , June 2018 in “International Journal of Pharmacological Research”

Hutchinson-Gilford Progeria Syndrome caused rapid aging due to a genetic mutation, with treatments to manage symptoms.

research Arginine Transferase Activity in Homogenates from Guinea Pig Hair Follicles

8 citations , November 1976 in “Journal of Investigative Dermatology”

research Alterations of Plasma Antioxidants and Mitochondrial DNA Mutation in Hair Follicles of Smokers

12 citations , January 2002 in “Environmental and Molecular Mutagenesis”

Smoking reduces antioxidants and causes DNA damage in hair follicles.

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community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 2 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Diffuse thinning is so brutal.

in Styling 71 upvotes 2 years ago

A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

community Wrinkly under eyes at 24?! Possible Minoxidil side effect?

in Minoxidil 18 upvotes 5 years ago

A user noticed wrinkling under one eye, possibly due to Minoxidil use. They seek advice on preventing or fixing this issue.

community 6 months on oral minox with no result

in Minoxidil 10 upvotes 3 years ago

A user who had taken oral minoxidil for 6 months without seeing any results and the advice given in response, which included trying microneedling in combination with topical minoxidil, as well as seeking a dermatologist's opinion.

community Tretinoin can make it worse!!!

in Chat 7 upvotes 2 years ago

Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

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