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Glossary Sebaceous Gland

small skin gland producing oily sebum for lubrication

A sebaceous gland, also known as an oil gland, is a small gland in the skin that produces sebum, an oily substance that helps to lubricate and protect the skin and hair. These glands are typically found in high concentrations on the face and scalp and are connected to hair follicles, releasing sebum through the hair follicle to the surface of the skin.

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Research

5 / 1000+ results

research Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line

36 citations , October 2009 in “Journal of Investigative Dermatology”

This study suggests that in SZ95 sebocytes, a pathway for DHT biosynthesis does not require testosterone as an intermediate, potentially impacting the treatment of androgen-sensitive skin conditions.

research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

181 citations , January 2019 in “Cell”

In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.

research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors

44 citations , July 2016 in “Stem Cells Translational Medicine”

This study demonstrated that cultured epidermal stem cells and skin-derived precursors can regenerate functional hair follicles and sebaceous glands in both mice and adult humans, suggesting potential for bioengineered skin substitutes.

research GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing

19 citations , January 2015 in “Scientific Reports”

This study found that the GPR39 receptor plays a novel role in accelerating wound healing in mouse skin, although it is not essential for skin development or homeostasis.

research Stem and progenitor cells in sebaceous gland development, homeostasis and pathologies

19 citations , March 2021 in “Experimental dermatology”

This review discusses recent progress in understanding the cellular mechanisms of sebaceous gland development and maintenance, emphasizing the role of stem and progenitor cells in related skin pathologies, and reports no new results.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Microneedling must reach the stem cells in the upper hair shaft

82 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

10 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for alopecia treatment. They enhance cell viability, maintain stemness, and induce hair growth without teratoma formation.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

11 upvotes 3 years ago

Fibrin hydrogels, when combined with stem cells, can induce hair follicle regeneration and show potential for treating alopecia. The study demonstrated successful hair growth in mice without adverse effects.

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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Epidermal Growth Factor

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