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In this study, pioglitazone treatment in patients with lichen planopilaris showed limited success, with significant improvement seen in only a minority of cases.

In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.

This case report suggests that spironolactone may induce prostate cancer proliferation in patients on abiraterone acetate, advising against its use for managing treatment-associated side effects in these individuals.

This study found that finasteride blocked the progesterone-induced increase in spike-wave discharges in rats, suggesting that this effect of progesterone is mediated by its metabolite allopregnanolone.

This study showed that spironolactone effectively reduces morbidity and mortality in moderate to severe heart failure with reduced ejection fraction, but its benefits in heart failure with preserved ejection fraction are less clear.

This study found that while glucagon-like peptide 1 receptor agonists report more incidents of suicide, hair loss, and aspiration compared to some other antidiabetic drugs, they did not meet the threshold for positive safety signals.

This case report describes the effective use of spironolactone for hirsutism in a patient with porphyria cutanea tarda.

This review discusses valproate-associated hair abnormalities, describing their common and benign nature, and outlines management strategies, though new clinical results are not provided.

This correction clarifies the affiliations of researcher D. Piomelli in a case report on symptom improvement in a chronic psychotic patient treated with finasteride, without presenting new research findings.

In this study, sustained-release sodium valproate showed high efficacy in achieving seizure remission for adults with focal and generalized epilepsy over one year, but side effects like weight gain and tremor were more frequent among heterozygous carriers of certain gene variants.

In this study, Proxalutamide significantly increased the rate of viral clearance and reduced clinical remission time in patients with mild to moderate COVID-19 compared to placebo.

This study found that isoallopregnanolone reduced stress-induced tic-like behaviors and sensorimotor gating deficits in a mouse model of Tourette syndrome, suggesting potential therapeutic properties comparable to existing treatments like haloperidol and finasteride.

Finasteride may help improve certain brain function issues linked to dopamine.

This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.

This review discusses the complex relationship between psychotropic medications and the skin, focusing on cutaneous side effects, dermatologic uses, and psychiatric disorders with skin manifestations, but reports no new findings.

This update provides information on new drug approvals but does not offer new clinical research findings.

In this study, the rate of hyperkalemia in women taking spironolactone for acne and related issues was low, but frequent monitoring of potassium trends during treatment may be advisable.

This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.

This study found that both topiramate and divalproex sodium were similarly effective in reducing headache frequency by over 50% among episodic migraine patients after three months of treatment.

This case report describes two postmenopausal women with Parkinson's disease who experienced reversible hair loss after using the dopamine agonists pramipexole and ropinirole.

The antidepressant escitalopram likely caused hair loss in a patient.

This report shares the authors' experience using spironolactone for treating acne in a PCOS clinic, but provides no new clinical results.

This case study describes a patient who developed mild eosinophilia and a skin rash after starting clozapine, which resolved without discontinuing the medication.

This study found that an intranasal gel containing risperidone-loaded glycethosomes significantly enhanced drug bioavailability and improved neuroprotective, antioxidant, and anti-inflammatory effects in schizophrenia-induced rats compared to oral therapies, suggesting a promising alternative for schizophrenic patients who struggle with adhering to oral medication.

In this study, clozapine reduced suicide-related behaviors in a schizophrenia-like mouse model, but its effects on exploratory behavior were counteracted by the neurosteroid inhibitor finasteride.