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Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Some hair protein genes evolved early and were adapted for use in hair follicles.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

Zebrafish with mutations similar to human Cantú Syndrome have heart cells with altered channel properties, making them a good model to study the condition.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Four botanical extracts were found to quickly attract neutrophils to wounded skin in zebrafish.

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

Neutrophils quickly respond to skin injury.

Neutrophils quickly move to the site of skin injury.

Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.

Finasteride reduces opioid use and withdrawal symptoms in animals.

Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.

Finasteride may help reduce opioid use.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.

New treatments for hair loss, fertility, and wound healing are being explored.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.

Gene regulation could revolutionize hair color by altering pigmentation from within.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.