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The April 2016 JEADV issue covered various dermatology topics, including psoriasis, psoriatic arthritis, mTOR inhibitors, autoimmune diseases, photodynamic therapy, viral DNA in skin diseases, chronic hand eczema, and female hair loss.

Stem cell niches support, regulate, and coordinate stem cell functions.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Red LED light helps mouse hair grow by increasing growth factors from skin cells.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Non-coding RNAs help control hair growth in cashmere goats.

Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.

Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.

Different forms of FGF5 either promote or inhibit hair growth.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Adipocytes can change into fibroblast-like cells to help with wound healing.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.