April 2021 in “Journal of Investigative Dermatology” A deep learning model was developed to help diagnose trichothiodystrophy by analyzing hair patterns.
This study found that a short-term treatment with all-trans retinoic acid may effectively stabilize platelet counts in idiopathic thrombocytopenic purpura patients experiencing fluctuations during thrombopoietin receptor agonist therapy.
1 citations
,
January 2024 in “International journal of molecular sciences” This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
May 2025 in “Clinical Cosmetic and Investigational Dermatology” In this clinical study, the researchers found that a standardized wheat polar lipid complex, in both oil and powder form, significantly reduced hair shedding and improved hair growth in 99 women with acute telogen effluvium over 56 to 84 days.
This study found that both trichoscopy and folliscopy are highly accurate for diagnosing telogen effluvium, though trichoscopy is simpler and faster to perform.
2 citations
,
February 2015 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that transplanting trichogenous dermal cells significantly enhanced the restoration of in vivo-damaged hair follicles in a nude rat model, with a combination of dermal papilla and sheath cells proving more effective than either cell type alone.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers introduced a mutation in mice to mimic Olmsted syndrome and found that the mutation caused hair loss due to impaired keratinocyte differentiation and depletion of hair follicle stem cells.
178 citations
,
October 2001 in “Genes & Development” This study found that the mammalian hairless gene encodes a corepressor protein that interacts with thyroid hormone receptors, providing insights into hair loss syndromes in humans and mice.
7 citations
,
August 2011 in “Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia” This study found that the modified wash test demonstrated high reliability in diagnosing and assessing the severity of androgenetic alopecia and telogen effluvium.
1 citations
,
October 2017 in “ecancermedicalscience” This study observed that the molecular structure of keratins in hair fibres' discrete transition zone differs in breast cancer patients, with altered lipid ester absorption bands reverting post-cancer removal.
January 2024 in “Lecture notes in networks and systems” In this study, a system was developed utilizing advanced image processing to analyze hair and scalp conditions, aiding professionals in diagnosing diseases like alopecia and monitoring treatment by extracting and comparing key parameters from microscopic images.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
46 citations
,
November 2007 in “Gene Expression Patterns” This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.
2 citations
,
January 2023 in “Journal of Education, Health and Sport” In this study, researchers reviewed current treatments for trichotillomania and found that psychotherapy, particularly cognitive-behavioral therapy like habit reversal training, is most effective, with some medications helping to alleviate symptoms, though further study is needed on their use.
1 citations
,
December 2022 in “Journal of applied biological chemistry” This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.
November 2024 in “Biophysical Chemistry” This study analyzed the swelling behavior of human hair during permanent waving treatment, finding that both the microstructure and macrostructure of intermediate filaments swell simultaneously at the initial stage, and while partially destructed by reduction, they are considerably restored through oxidation.
August 2026 in “The Journal of Dermatology” In this review, the authors summarize recent findings on dermal white adipose tissue (dWAT), highlighting its crucial role in the hair follicle microenvironment by regulating inflammation and immune responses, thus influencing hair regeneration.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses Truman Plus Male Enhancement, a testosterone booster, emphasizing its potential benefits for sexual health and energy, but does not report any new clinical results.
39 citations
,
February 1990 in “The journal of cell biology/The Journal of cell biology” This study identified trichohyalin as an early differentiation marker in hair follicles, with potential structural roles related to alpha-helical formations, based on the partial characterization of its cDNA in sheep.
May 2017 in “InTech eBooks” This article describes various hair and scalp examination techniques, including noninvasive, semi-invasive, and invasive methods, noting that trichoscopy is a simple, well-accepted, noninvasive technique for evaluating hair loss patients and monitoring treatment.
October 2022 in “International Journal of Research in Dermatology” This study suggests that hormonal disturbances play a role in female pattern hair loss and that trichoscopy may be a useful tool for diagnosis and differentiation from other conditions.
March 2009 in “International Society of Hair Restoration Surgery” This article reviews dermatopathology perspectives on diagnosing hair loss conditions and reports no new clinical findings.
67 citations
,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.
April 2025 in “Journal of Investigative Dermatology” This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the benefits of Truman Plus Male Enhancement for testosterone levels and sexual health, but it does not present any new clinical study results.
2 citations
,
January 1908 in “Journal of the American Medical Association” Fear of hair-related issues causes significant mental distress, especially in high-stress women.
1 citations
,
January 2013 in “PubMed” In this study, treating hair with thioglycolic acid was found to alter disulfide bond patterns in keratin-associated proteins, shifting them from an ellipsoidal to a near-spherical shape.
7 citations
,
May 2024 in “Life” This study found no significant laboratory differences between Caucasian adults with non-cicatricial alopecia and healthy controls, but reported that affected individuals were significantly younger, suggesting that lifestyle and diet might contribute to early hair loss risk.
6 citations
,
December 2021 in “International Journal of Endocrinology” This study found that the INSR His1058 C/T SNP does not increase the risk of developing PCOS among Kashmiri women.
3 citations
,
November 2021 in “Stress” This study found that school-related stress increases hair cortisol in girls and alters hair testosterone and cortisol levels in boys, indicating gender-specific hormonal responses to environmental changes.