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Human skin can make serotonin and melatonin, which help protect and maintain it.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Telocytes might help with skin repair and regeneration.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

SHBG may be a useful early indicator and treatment target for PCOS.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Hydrogels could lead to better treatments for wound healing without scars.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

Hair follicle stem cells can turn into various cell types and help repair nerves.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.