77 citations
,
August 2025 in “Signal Transduction and Targeted Therapy” This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
1 citations
,
May 2026 in “Signal Transduction and Targeted Therapy” This review highlights the promising role of stem cell therapy in treating resistant diseases, while also addressing the challenges in production and clinical application, emphasizing the need for standardized manufacturing and quality assurance to enhance efficacy and safety in clinical translational research.
4 citations
,
May 2014 in “Biochemical Society Transactions” This review discusses environmental reprogramming and the plasticity of epithelial cells, emphasizing their potential for new cell therapy approaches; it reports no new experimental results.
54 citations
,
January 2023 in “Signal Transduction and Targeted Therapy” This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.
41 citations
,
October 2000 in “Dermatologic clinics” This paper reviews hair structure and damage from grooming and cosmetic exposure but reports no new clinical findings; it suggests collaboration between dermatologists and cosmetic chemists to improve hair care products.
May 2017 in “InTech eBooks” This review outlines various complications associated with hair transplantation, noting that while most are mild and manageable, serious complications like necrosis can occur if proper care is not taken.
103 citations
,
June 2007 in “Endocrinology and Metabolism Clinics of North America” This article discusses treatment options for androgenetic alopecia, noting that medical interventions like finasteride and minoxidil can halt and partially reverse hair loss in mild to moderate cases, especially when combined with surgery.
32 citations
,
November 2012 in “Aesthetic Surgery Journal” This article reviews advancements in hair restoration, highlighting improvements in surgical techniques and patient satisfaction, but reports no new clinical results.
5 citations
,
November 2019 in “Dermatology and therapy” This review discusses the use of beard hair as a donor source for hair transplantation in hirsute patients and highlights the lack of extensive studies on its efficacy and safety in East Asian populations.
1 citations
,
November 2002 in “Neurosurgery Clinics of North America” This article reviews the role of androgens in male pattern hair loss and its emotional impact, but reports no new clinical findings.
69 citations
,
August 1999 in “Developmental biology” This study found that ectopic expression of Whn in transgenic mice caused impaired differentiation in epidermis and hair follicles, with hair growth defects and severe urinary tract issues leading to hydronephrosis.
12 citations
,
January 2018 in “Journal of Drug Delivery Science and Technology” This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.
6 citations
,
May 1997 in “Journal of Dermatological Science” This study found that a gene from hamster flank organs is indirectly regulated by androgens, despite lacking direct androgen responsive elements, indicating involvement of androgen-dependent transcription factors.
157 citations
,
October 2003 in “Development” This study found that different stabilizing mutations in Aux/IAA proteins affect root hair development in Arabidopsis by disrupting the auxin response and suggest a model where the relative abundance of these proteins determines root hair initiation.
28 citations
,
December 2006 in “Clinical lung cancer” This review outlines various non-rash skin toxicities associated with novel targeted anticancer therapies and provides guidelines for their early diagnosis and management, but reports no new clinical results.
1 citations
,
July 2012 in “Nasza Dermatologia Online” This case report suggests that immune responses, along with hair traction, may play a role in the etiology of central centrifugal cicatricial alopecia.
January 1998 in “Lasers in Surgery and Medicine” This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.
120 citations
,
October 2007 in “Clinical Interventions in Aging” This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.
72 citations
,
September 1997 in “Dermatologic Surgery” This review discusses follicular transplantation for hair restoration, highlighting the importance of evaluating patient suitability and careful planning to achieve excellent cosmetic outcomes, but reports no new research findings.
54 citations
,
August 2009 in “Dermatologic Surgery” This review outlines the steps of contemporary hair transplantation surgery, including the roles of medications and nonsurgical options, but it reports no new clinical findings.
32 citations
,
September 2017 in “Journal of the American Academy of Dermatology” In this study, researchers reported that oral isotretinoin effectively treated facial papules in frontal fibrosing alopecia, with histopathologic findings suggesting the involvement of elastic fibers and sebaceous glands in papule formation beyond perifollicular inflammation.
30 citations
,
March 2006 in “Dermatologic Surgery” In this study of men with androgenetic alopecia, daily finasteride 1 mg alongside hair transplant improved scalp hair density and growth of nontransplanted hair compared to placebo over 48 weeks.
24 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses potential complications in surgical hair restoration and emphasizes the importance of both patient and physician actions in minimizing these risks; it reports no new results.
23 citations
,
October 2005 in “Dermatologic Surgery” This study found that finasteride 1 mg daily, taken before and after hair transplant surgery, significantly improved scalp hair coverage and density in men with androgenetic alopecia compared to placebo.
19 citations
,
April 2010 in “Journal of Dermatological Treatment” This study found that partial follicular units extracted from the donor area can survive and regenerate new hairs at their original site and when transplanted, effectively creating two hair follicles from one.
11 citations
,
June 2005 in “Journal of Cosmetic Dermatology” Lasers in hair transplantation show promise but are not yet standard, with current methods causing some side effects and needles still being preferred for creating recipient sites.
11 citations
,
August 2004 in “Facial Plastic Surgery” This review describes endoscopic techniques for rejuvenating the upper two-thirds of the face, highlighting their safety, reliability, and fewer complications compared to traditional open procedures, and reports no new clinical results.
9 citations
,
January 2015 in “Current problems in dermatology” This review discusses partial longitudinal-follicular unit transplantation (PL-FUT) for hair loss and notes its potential to multiply hair follicles while preserving donor areas, but reports no new clinical results.
5 citations
,
February 2018 in “Experimental Dermatology” This study describes a method inspired by hair transplantation techniques to efficiently isolate eccrine sweat glands from human scalp hair grafts, potentially facilitating further research into their function.
4 citations
,
August 2018 in “Journal of Cosmetic Dermatology” In this study, wound closure tension following strip surgery for hair restoration varied by strip width, highlighting the importance of minimizing tension to achieve better scarring outcomes.