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Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Increasing sebum production might help reduce fat and improve metabolism.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

Fat cells are important for tissue repair and stem cell support in various body parts.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Women with PCOS are much more likely to have sleep problems and should be checked for them.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Polycystic ovary syndrome causes chronic inflammation affecting all body systems, but proper nutrition, exercise, and supplements can improve the condition.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

More severe hair loss links to thicker heart fat, suggesting possible heart disease risk.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.