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PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

Proper nutrition can help manage PCOS symptoms and improve overall health.

Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Medications for PCOS don't seem to raise heart disease risk.

Olive leaf compound oleuropein helps grow hair in mice.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Treating hyperprolactinemia can help manage PCOS symptoms.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Fat-related cells are important for initiating hair growth.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Fat cells help recruit healing cells and build skin structure during wound healing.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Researchers found 15 new genetic links to skin traits in Japanese women.