research Bone vs. Fat: Embryonic Origin of Progenitors Determines Response to Androgen in Adipocytes and Osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
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research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Premature Adrenarche, Polycystic Ovary Syndrome, and Intrauterine Growth Retardation: Does a Relationship Exist?
Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research A Review and Meta-Analysis of the Prevalence and Health Impact of Polycystic Ovary Syndrome Among Medical and Dental Students
PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.
research Retinol-Binding Protein 4, Leptin, and Insulin Resistance in Idiopathic Hirsutism and Hirsute Women with Polycystic Ovary Syndrome
Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Exploring the Impact of Ovariectomy on Hair Growth: Can Ovariectomized Mouse Serve as a Model for Investigating Female Pattern Hair Loss in Humans?
research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research Association Between Androgenetic Alopecia and Metabolic Syndrome – A Case Control Study
Men with androgenetic alopecia may have a higher risk of metabolic syndrome.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Protein Kinase C Downregulation Upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease
Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.
research Posttest: Expiration Date: October 2011
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Treatment of Lymphocutaneous and Visceral Sporotrichosis with Fluconazole
Fluconazole is somewhat effective for skin-related sporotrichosis but less so for severe forms, and should be a backup treatment.
research The Frequency of Visceral and Phenotypic Markers in Patients with the Combination of Undifferentiated Connective Tissue Disease and Gastroesophageal Reflux Disease
Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.
research Broiler Chicken Meat Extract Increases Body Weight, Visceral Fat Mass, and Hair Production in Young Male Wistar Rats (Rattus Norvegicus)
Broiler chicken meat extract increases body weight, visceral fat, and hair production in young male Wistar rats.
research The Influence of Obesity on Androstenedione to Testosterone Ratio in Women with Polycystic Ovary Syndrome and Hyperandrogenemia
Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
research Treatment of Lipodystrophy with Troglitazone
Troglitazone increases subcutaneous fat in lipodystrophy patients.
research Neonatal Inhibition of Androgen Activity Alters the Programming of Body Weight and Orexinergic Peptides Differentially in Male and Female Rats
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
research Body Composition Parameters, Carotid Intima Media Thickness and Epicardial Fat Thickness in Male Patients with Androgenetic Alopecia
Men with male pattern baldness had higher body fat and obesity-related measurements but similar heart fat and artery thickness compared to healthy men.