May 2006 in “Dermatologic Surgery” This study found that multi-hair follicles naturally orient perpendicular to the radial line from the crown whirl, suggesting that perpendicular transplantation of grafts could replicate this natural appearance.
November 2002 in “Dermatologic Surgery” This review discusses the surgical methods of hair restoration, highlighting the density benefits of scalp reduction and rotation, but reports no new clinical findings.
September 2002 in “Dermatologic Surgery” The author reports that an evaluation system for assessing candidacy in alopecia-reducing procedures significantly decreased unsuitable surgeries while maintaining consistently good outcomes.
2 citations
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September 2020 in “Hair transplant forum international” This study reports that a new multi-slit knife for hair transplant procedures reduces surgical time and increases precision by enabling quick creation of equidistant "brick-pattern" sagittal slits.
July 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study introduced the BASP classification, a new system for categorizing pattern hair loss in both men and women, and applied it to analyze 2213 Korean subjects.
3 citations
,
April 2016 in “PubMed” This study found that a twice-daily regimen of 5% minoxidil foam combined with a botanical hair solution significantly improved hair growth and appearance in men with mild to moderate androgenic alopecia over 12 weeks.
January 2026 in “Dermatologic Therapy” This study found that in patients with female androgenetic alopecia, mesodermal injection of 0.5% minoxidil was more effective in increasing hair density and improving hairline height than topical 2% minoxidil, with comparable safety over 16 weeks.
This study reports that topical 5% minoxidil solution significantly increased total hair counts and hair diameter in Korean men with androgenetic alopecia over 24 weeks and was well tolerated.
12 citations
,
May 2021 in “Clinical Interventions in Aging” This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.
3 citations
,
January 2021 in “Plastic and Aesthetic Research” This study found that hair mass index can effectively link hair productivity with clinical scalp coverage perception, suggesting its potential usefulness in diagnosing hair loss patterns and responses to treatment.
March 2025 in “Cosmetics” This study found that combining PRP with topical minoxidil or finasteride significantly improved hair density and thickness, with patient satisfaction highest for multiple treatment combinations and longer durations.
February 2024 in “Scientific Reports” In this retrospective cohort study, 87.1% of pediatric patients with chemotherapy-induced alopecia experienced clinical improvement after treatment with minoxidil or combination therapy with CYP, with the combination therapy showing greater hair thickness and minimal adverse effects.
June 2023 in “Aesthetic Plastic Surgery” This study introduces the PRECISE scale, a quantitative tool to classify androgenetic alopecia, aiming to improve planning and outcomes for hair transplantation surgeries by evaluating the whole hairless and thinning areas.
50 citations
,
May 1999 in “Journal of Reconstructive Microsurgery” This study concluded that microsurgical reconstruction is a reliable method to achieve stable coverage of large, complex scalp defects, although cancer control rates were poor.
23 citations
,
October 2005 in “Dermatologic Surgery” This study found that finasteride 1 mg daily, taken before and after hair transplant surgery, significantly improved scalp hair coverage and density in men with androgenetic alopecia compared to placebo.
15 citations
,
January 2020 in “BioMed Research International” In this study of patients with androgenetic alopecia, botulinum toxin type A was found to significantly increase hair counts and improve hair density and coverage, with enhanced results observed when combined with oral finasteride, revealing a safe and effective treatment approach without adverse effects.
7 citations
,
June 1992 in “The Journal of Dermatologic Surgery and Oncology” This discussion reviews hair transplantation as a treatment for thinning, hairline restoration, or scar coverage in females, offering no new clinical findings.
5 citations
,
August 2013 in “Facial plastic surgery clinics of North America” This article discusses managing extensive hair loss with limited transplant options and suggests a frontal forelock-type pattern is effective for both already bald men and younger patients at risk; it reports no new clinical results.
29 citations
,
September 2012 in “Dermatologic Clinics” This article reviews the causal mechanisms of hair follicle disorders, focusing on inflammation, genetics, environment, and hormones, but it reports no new clinical results.
6 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This review discusses the advancements in surgical hair restoration over the past decade, focusing on optimizing follicular unit transplantation for better aesthetic results, but it reports no new clinical findings.
May 2024 in “Proteome science” This study found that the PLEE method increased hair protein extraction efficiency threefold and that bleaching hair reduced the coverage of keratin and associated proteins, leading to poorer hair quality, though it did not affect the overall protein identification.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
15 citations
,
May 2020 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.
13 citations
,
May 2004 in “Dermatologic Surgery” This article outlines a method for achieving natural-looking hair direction and density in hair transplants using specific parting and incision techniques, without accelerating hair loss in the recipient area.
3 citations
,
May 2006 in “Dermatologic Surgery” This study found that multi-hair follicles in nonbald men are primarily oriented perpendicular to the radial line from the crown whorl, suggesting perpendicular transplant grafts might mimic natural appearance.
June 2004 in “Dermatologic Surgery” This study outlines a technique for hair transplantation that maintains natural hair flow and density by mimicking natural hair direction and angle without accelerating hair loss in the recipient area.
September 2022 in “Scientific Reports” This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.
370 citations
,
September 1999 in “The New England Journal of Medicine” This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.
72 citations
,
September 1997 in “Dermatologic Surgery” This review discusses follicular transplantation for hair restoration, highlighting the importance of evaluating patient suitability and careful planning to achieve excellent cosmetic outcomes, but reports no new research findings.
31 citations
,
October 2002 in “Dermatologic Surgery” This article reviews expert opinions on combining pharmacologic treatments like minoxidil with hair transplantation, reporting improved hair density and regrowth in patients with partially functioning follicles.