This case study documented that a 67-year-old woman with Netherton syndrome experienced significant improvements in skin inflammation, pruritus, and hair growth after treatment with dupilumab, addressing symptoms of the syndrome and showing promising results for resolving "bamboo" hair.
September 2016 in “Journal of Dermatological Science” Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.
71 citations
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February 2006 in “Clinics in Dermatology” This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.
18 citations
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October 1978 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that excess vitamin A induced stable glandular morphogenesis and mucous metaplasia in embryonic mouse vibrissa follicles, even after switching to standard medium.
1 citations
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June 2025 in “Journal of Allergy and Clinical Immunology Global” This study describes the case of a young boy with Netherton syndrome who showed significant improvements in skin inflammation, quality of life, and hair growth after receiving dupilumab, with a marked decrease in serum IgE levels observed following treatment.
12 citations
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January 2013 in “Indian Journal of Dermatology” This case report on a 13-year-old boy with monilethrix observed slight improvement after a two-month trial of oral N-acetyl cysteine, but overall hair density did not improve further.
23 citations
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January 2023 in “Journal of Developmental Biology” In this study, researchers discussed how specific protein interactions in reptile skin allow for the development of protective structures like scales and scutes, which facilitated reptiles' adaptation to terrestrial environments.
10 citations
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January 1985 in “PubMed” This study observed that hair zinc concentration in normal infants decreased from birth to eight months before rising again at twelve months, with lower levels associated with hair loss and diaper rash.
47 citations
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May 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses normal skin changes during pregnancy such as pigmentary and glandular alterations, highlighting the need for physician awareness to avoid unnecessary treatments, and reports no new clinical findings.
2 citations
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May 1991 in “PubMed” This article reviews naevus comedonicus, highlighting potential treatments like retinoic acid application and surgical intervention, but reports no new clinical findings.
1 citations
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February 2023 in “All Life” This study identified proteins involved in hair follicle formation in cashmere goat embryos, highlighting potential signaling factors that may drive hair follicle initiation and cashmere growth.
1 citations
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October 2023 in “PROTOPLASMA” December 2004 in “PLoS ONE” In this study, the Foxn1(-/-) nude phenotype was associated with an altered regulation of epithelial progeny in skin, offering a valuable model for investigating stem cell niche maintenance and regulation.
6 citations
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January 2008 in “Indian Journal of Dermatology” This case report describes a rare autosomal dominant hair shaft disorder, monilethrix, observed in three consecutive generations of a family, with gradual improvement noted with age.
This article reviews the history and characteristics of the rare nude phenotype SCID, primarily distinguished by severe T cell immunodeficiency and notable skin and hair abnormalities, but reports no new clinical findings.
1 citations
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June 2016 in “Medicina” This article reviews monilethrix, a rare genetic hair disorder causing brittle hair and alopecia, and emphasizes the need for clinical diagnosis and characteristic tricoscopic findings.
1 citations
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July 2018 in “JAMA dermatology” This abstract contains navigation and subscription information for JAMA Dermatology and reports no new clinical findings.
96 citations
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January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
6 citations
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February 2016 in “American Journal of Dermatopathology” This case study reports on an 11-year-old boy with woolly hair nevus, featuring twisted hair shafts and an abnormal hair cuticle, alongside epidermal nevi on his face and back.
In this case report, a 67-year-old woman with Netherton syndrome experienced significant improvement in skin inflammation, pruritus, and hair growth after treatment with dupilumab, suggesting potential benefits for addressing both cutaneous and hair manifestations of the condition.
34 citations
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January 1998 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This report describes four trichoblastoma cases rich in Merkel cells, suggesting these tumors may mimic fetal skin development where Merkel cells are numerous.
January 2024 in “JAAD case reports” Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.
6 citations
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August 2012 in “The Journal of Pediatrics” This case report describes a 12-year-old girl diagnosed with monilethrix, characterized by fragile, beaded hair shafts, with no effective treatment currently available.
40 citations
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February 1990 in “Journal of The American Academy of Dermatology” This study presents the first reported case of woolly hair nevus appearing during adolescence, with significant improvement observed 5 years later and structural changes in the hair documented.
2 citations
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January 2014 in “Indian dermatology online journal” This report describes a case of isolated congenital atrichia combined with nevus flammeus.
December 2025 in “Clinical Case Reports” In this study, researchers reported that dermoscopic examination of eyebrow hairs can help in the early diagnosis of Netherton syndrome in children by detecting trichorrhexis invaginata, facilitating prompt counseling and care while awaiting genetic test results.
January 2006 in “Durham e-Theses (Durham University)” This study reports for the first time on the expression patterns of Id2 and Id3 proteins in developing hair follicles, suggesting a significant role for these proteins in hair follicle development and epithelial-mesenchymal interactions.
24 citations
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June 2011 in “International Journal of Dermatology” This review summarizes physiologic skin changes during pregnancy and specific pregnancy-related dermatoses but reports no new clinical results.
March 2026 in “Journal of Investigative Dermatology” 2 citations
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January 2002 in “Clinics in Dermatology” This review details the characteristics, associations, and differential diagnoses of vitiligo and reports no new clinical findings.