37 citations
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September 2018 in “The Journal of Clinical Endocrinology and Metabolism” This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.
13 citations
,
November 1959 in “Annals of the New York Academy of Sciences” 7 citations
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January 2019 in “Journal of clinical medicine research” This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.
5 citations
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June 2024 in “Cureus” This scoping review suggests there is a relationship between polycystic ovarian syndrome and vaginal microbiome dysbiosis, potentially linked to decreased Lactobacillus and increased pathogenic species.
5 citations
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February 2020 in “Journal of pediatric & adolescent gynecology” In this study, recurrent vaginal bleeding in pre-pubertal girls was most often not linked to hormonal abnormalities, with two cases caused by foreign bodies that were resolved upon removal.
In this study, a spayed adult female dog with recurrent vaginitis and cystitis due to bone structures in the vaginal canal was successfully treated with manual removal and medication.
2 citations
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June 2010 in “Medicina de Familia SEMERGEN” The girl's "dandruff" was actually harmless hair casts, not a hygiene issue.
9 citations
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December 2009 in “Cancer Research” This study concluded that both vaginal TEST and Estring may be effective for treating vaginal dryness in breast cancer patients on aromatase inhibitors, with adverse events being rare and manageable.
6 citations
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April 2021 in “Journal of Mind and Medical Sciences” In this study, most women who experienced both vaginal and Caesarean births preferred and recommended natural delivery, suggesting the need for careful, individualized evaluation of birth conditions.
6 citations
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September 2020 in “Journal of Mind and Medical Sciences” This study found that vaginal surgical interventions for genital prolapse or urinary incontinence did not significantly alter the quality of sexual life in women, with a portion reporting improvement and others experiencing no change or decreased libido.
3 citations
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May 2020 in “Gynecology Obstetrics and Reproductive Medicine” In this study, no association was found between bacterial vaginosis and skin disorders in patients with autoimmune antibody positivity.
2 citations
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July 2023 in “Obstetrics & Gynecology” In this study, imiquimod was found to increase regression of cervical intraepithelial neoplasia compared to placebo, though it commonly caused side effects that rarely led to treatment discontinuation.
July 2013 in “Revista da Universidade Vale do Rio Verde” In this study on short-term flutamide treatment in mice, no significant changes were observed in estrous cycle phases, but further research is needed to explore potential reproductive effects.
4 citations
,
March 1999 in “International Journal of STD & AIDS” This report details a case of severe recurrent bacterial vaginosis in a woman with Netherton's syndrome.
October 2022 in “Amplla Editora eBooks” The document's conclusion cannot be provided because the document is not accessible or understandable.
1 citations
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April 2024 in “Acta Biochimica et Biophysica Sinica” This study categorizes the human fetal vaginal epithelium into four areas with distinct transcriptomic profiles, aiding potential advancements in vaginal reconstruction and drug delivery.
March 2025 in “Laboratory Investigation” This study examined the clinicopathologic features of mesothelioma of the tunica vaginalis testis in 14 patients, finding that the disease mostly presented as epithelioid type, with a propensity for high-grade tumors, and BAP1 and MTAP loss was uncommon.
January 2025 in “Case Reports in Hematology” In this case report, a 17-year-old female with symptoms such as vaginal bleeding and weight loss was diagnosed with B-cell acute lymphoblastic leukemia, emphasizing the importance of considering hematological malignancies in young patients with unusual presentations, as early diagnosis can significantly improve outcomes.
January 2008 in “Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu” This study found that selecting human vaginal mucosa stem cells by adhesion to type Ⅳ collagen for 20 minutes and culturing them with feeder layer and epidermal total culture media was most effective in maintaining their characteristics.
March 2026 in “Panacea Journal of Medical Sciences” This study evaluated 23 cases of MRKH syndrome undergoing neo-vaginal reconstruction using islanded pudendal thigh flaps, finding a 100% flap survival and patency rate, along with satisfactory functional and aesthetic outcomes despite minor issues like hair growth in some patients.
23 citations
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March 2019 in “Plastic and Reconstructive Surgery – Global Open” This study found that BMI was not a significant factor in predicting surgical complications for transgender patients undergoing penile inversion vaginoplasty, suggesting obese patients can safely undergo gender affirmation surgery.
February 2026 in “Libri Oncologici Croatian Journal of Oncology” The review found that imiquimod is a promising non-invasive treatment for HPV-related neoplasias, particularly effective for vulvar lesions, but notes that more research is needed to optimize its use.
237 citations
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January 2010 in “The Journal of Sexual Medicine” The authors updated recommendations on diagnosing and treating women's sexual dysfunctions, emphasizing a comprehensive assessment approach, while noting the need for further multidisciplinary research.
83 citations
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August 2018 in “BJOG” This commentary discusses the feasibility and challenges of uterine transplantation for transgender women, emphasizing anatomical, hormonal, and ethical considerations without reporting new clinical results.
75 citations
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February 2016 in “The Journal of Sexual Medicine” This review highlights the efficacy of transdermal testosterone therapy in improving sexual function in women with hypoactive sexual desire disorder, though approved formulations and long-term safety data are limited.
46 citations
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January 2007 in “The European Journal of Contraception & Reproductive Health Care” This review discusses the increased risk of venous thromboembolism associated with combined hormonal contraceptives, particularly noting higher risks with certain progestins like desogestrel, gestodene, and cyproterone acetate, but reports no new clinical findings.
41 citations
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February 1970 in “Archives of Dermatology” This review discusses various cutaneous side effects potentially linked to oral contraceptive use but provides no new clinical results, emphasizing the need for more evidence in certain associations.
28 citations
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March 2010 in “Clinics in dermatology” This review details historical advancements in understanding and treating superficial fungal infections, with notable milestones in identifying causative agents and developing effective treatments, but it reports no new findings.
18 citations
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August 2019 in “Clinical breast cancer” This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.
13 citations
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December 2010 in “Annales de Dermatologie et de Vénéréologie” This retrospective study in Morocco confirms that Stevens-Johnson and Lyell syndromes lead to severe ocular and unsightly mucocutaneous sequelae, significantly affecting patients' social and professional integration.