1 citations
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January 2017 in “Pharmaceutica Analytica Acta” This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
14 citations
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December 2011 in “Archives of Dermatological Research” This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.
4 citations
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January 2016 in “Journal of analytical & bioanalytical techniques” This study evaluated a hair growth gel with Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum extracts, demonstrating consistent homogeneity, 5 α-reductase inhibitory activity, and no skin irritation.
This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.
January 2024 in “International Journal of Pharmacognosy and Pharmaceutical Research” This review highlights the potential of plant-derived molecules like Epigallocatechin-3-Gallate and Ginsenosides to promote healthy hair growth by enhancing nutrient supply and blood flow to the scalp, and notes their growing role in natural hair care product development.
August 2021 in “International Journal of Research in Dermatology” This study observed that Amarantha hair oil contains β-sitosterol, which is suggested to promote hair growth.
This study found that aeroponic cultivation significantly increased the growth and bioactive compound content of Cannabis Sativa roots compared to soil cultivation.
19 citations
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April 2020 in “Journal of ethnopharmacology” This study found that nut oil from Prunus mira promoted hair growth in mice, potentially through the Wnt/β-catenin signaling pathway.
8 citations
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May 2024 in “Advanced NanoBiomed Research” This review examines advancements in lipid and inorganic nanocarriers, such as liposomes and inorganic nanoparticles, for transdermal drug delivery, noting enhanced absorption and stability but acknowledging that few have reached clinical use.
December 2024 in “Plant Science Today” This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
July 2023 in “International journal of life science and pharma research” In this study, a herbal hair cream containing extracts from Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum was developed, showing promising in-vitro inhibition of the 5α-reductase enzyme and potential benefits for alopecia treatment.
7 citations
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September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.
August 2026 in “Plant Science Today” This review synthesizes data on Eclipta alba, highlighting its traditional use for liver, skin, and general health, supported by preclinical evidence of hepatoprotective and other beneficial activities, while noting the need for more rigorous toxicological and clinical safety studies to substantiate its therapeutic applications.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
February 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that administering 1000 mg/kg of LSFP significantly reduced serum FSH and LH levels and testicular index in male Wistar rats, while lower doses showed no such effect.
18 citations
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January 2007 in “Pharmaceutical Biology” This study found that petroleum ether extracts of Citrullus colocynthis reduced hair growth initiation time and advanced more hair follicles to the anagen phase in albino rats compared to untreated controls and minoxidil.
5 citations
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September 2009 in “Journal of Complementary and Integrative Medicine” This study found that the petroleum ether extract of Citrullus colocynthis fruit and an isolated steroidal compound may reduce prostatic hyperplasia in rats induced by testosterone, suggesting potential use in managing androgen-dependent conditions.
January 2025 in “International Journal of Advanced Research in Science Communication and Technology” This review summarizes the pharmacological and therapeutic uses of Calotropis gigantea latex, noting its traditional applications in treating skin diseases, wounds, and asthma, as well as its potential in addressing cancer, diabetes, and cardiovascular diseases due to its rich bioactive compound content.
7 citations
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March 2024 in “Scientific Reports” This study reports that the new neighborhood face index (NFI) demonstrates a remarkably high correlation with the physiochemical properties of benzenoid hydrocarbons, highlighting its potential as a predictive tool.
6 citations
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March 2022 in “Nusantara Bioscience” This study evaluated the thrombolytic potential of Moringa oleifera leaves and flowers, finding significant in vitro clot lysis activity at a concentration of one mg/ml, which suggests possible use in preventing athero-thrombotic cardiovascular diseases, although further research is needed to identify the active components.
3 citations
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May 2024 in “Journal of Drug Delivery and Therapeutics” This review examines the therapeutic potential of Aftimoon (Cuscuta reflexa), focusing on its pharmacological properties and traditional uses in Unani medicine for various ailments, and highlighting its range of biological activities, including antioxidant and anti-inflammatory effects.
3 citations
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March 2016 in “Phytotherapy Research” In laboratory tests, this study found that a novel natural composition targeting 5-alpha reductase and inflammatory pathways reduced disease-related markers in androgenetic alopecia and benign prostatic hyperplasia more effectively than finasteride.
1 citations
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May 2025 in “International Journal of Advanced Biochemistry Research” This review discusses the phytochemical, pharmacological, and medicinal properties of Hibiscus rosa sinensis Linn. and reports no new clinical findings.
January 2012 in “Human health handbooks” This article explores the role of ethno-medicinal plants in hair growth and loss treatments but reports no new clinical findings, highlighting Ayurveda's long-standing use in addressing hair-related issues.
May 2026 in “International Research Journal of Modernization in Engineering Technology and Science” This study developed an herbal shampoo using traditional plant ingredients, demonstrating its effective cleansing, conditioning, and protective properties while minimizing synthetic chemicals, aligning with consumer preferences for natural and sustainable personal care products.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
26 citations
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April 2019 in “Journal of Cosmetic Dermatology” This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.
17 citations
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December 2015 in “BMC Complementary and Alternative Medicine” This study found that Avicennia marina extract significantly inhibited 5α-reductase type 1 activity in human hair dermal papilla cells, suggesting its potential use for treating androgenic alopecia.
15 citations
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May 2004 in “Facial Plastic Surgery Clinics of North America” This article reviews pharmacologic treatments for pattern hair loss and emphasizes integrating them with surgical and nonmedical options, but it does not present new clinical findings.