In Vitro Thrombolytic Activity of Moringa Oleifera

    March 2022 in “ Nusantara Bioscience ”
    BHAVIKA KUNWAR, Vartika Jain, S. K. VERMA
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    Studysummary This study evaluated the thrombolytic potential of Moringa oleifera leaves and flowers, finding significant in vitro clot lysis activity at a concentration of one mg/ml, which suggests possible use in preventing athero-thrombotic cardiovascular diseases, although further research is needed to identify the active components. Our plain-language summary of this paper — not a Tressless recommendation.
    The study assessed the in vitro thrombolytic activity of Moringa oleifera leaves and flowers, revealing significant clot lysis potential. Methanolic extracts of leaves (MEL-I and MEL-II) showed clot lysis activities of 36.64% and 41.40%, respectively, while flower extracts (MEF-I and MEF-II) demonstrated 19.07% and 20.52% clot lysis at a concentration of 1 mg/ml. These results suggested that M. oleifera could potentially be used to prevent athero-thrombotic cardiovascular diseases. The study highlighted the need for further research to isolate the bioactive molecule responsible for this thrombolytic effect.
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