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Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.

A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Long-term finasteride use doesn't change bone density or metabolism.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Finasteride reduces hair growth and is safe for women with excessive hair.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.