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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Immune checkpoint inhibitors used in cancer therapy can cause hair loss, and understanding this can help manage the side effect.

A woman developed severe bladder inflammation after cancer treatment with Cytoxan.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

Various drugs caused different skin reactions, including allergic and inflammatory responses.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Ruby laser hair removal significantly reduces hair density.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Telocytes in the scalp may help with skin regeneration and maintenance.

Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.

Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.

The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.