Cutaneous Drug Reaction Case Reports
January 2003
in “
American Journal of Clinical Dermatology
”
TLDR Various drugs caused different skin reactions, including allergic and inflammatory responses.
The document presents a series of case reports on adverse skin reactions caused by various drugs. A 57-year-old woman developed eosinophilic pustular folliculitis from allopurinol and timepidium bromide, which improved with corticosteroids after discontinuing the drugs. A 35-year-old man experienced alopecia areata from cyclosporine, which persisted even after stopping the medication. Other cases included Sweet's Syndrome from BCG vaccination, gangrene from hydroxycarbamide, Stevens-Johnson Syndrome from imatinib mesylate, and melanoderma from indapamide. Additionally, the document reports first cases of hypersensitivity to pegylated interferons in two men, leucocytoclastic vasculitis in a 69-year-old woman from pergolide, pemphigus vegetans in a 59-year-old man from povidone iodine, urticaria in a 36-year-old woman from terbutaline, and acute generalized exanthematous pustulosis in a 52-year-old woman from trimetazidine. These cases were confirmed as novel by searches in AdisBase, Medline, and the WHO Adverse Drug Reactions database, highlighting the importance of recognizing drug-induced skin disorders.